Can We Prevent Aging?

People are living longer. In 1970, the average life expectancy at birth was 70.8 years; in 2000, it was 76.9 years; and by 2030 is it estimated that the “oldest-old,” age 85 and older, could grow to 10 million people.Views on aging are also changing. It no longer necessarily means physical decline and illness—in the last two decades, the rate of disability among older people has declined dramatically.

The National Institute on Aging (NIA), part of the Federal Government’s National Institutes of Health (NIH), investigates ways to support healthy aging and prevent or delay the onset of diseases that disproportionately affect us as we age. These studies not only may increase what is known as “active life expectancy”—the time of advancing years free of disability—but also may promote longevity. NIA’s research includes hormone and dietary approaches, including calorie restriction.

Results from NIA-sponsored studies and others are likely to improve our understanding of the benefits and risks of hormone supplements, calorie restriction, and other interventions to promote healthy aging. This tip sheet provides an overview of what we know about hormone supplements and calorie restriction and the research needed to learn more. Until we have a better understanding, it is a good idea to be skeptical of claims that hormone or other supplements can solve your age-related problems. Instead, focus on what is known to help promote healthy aging: healthy eating and physical activity.

What Is a Hormone?

The word “hormone” comes from the Greek word, hormo, meaning to set in motion. Hormones are chemical messengers that set in motion different processes to keep our bodies working properly. For example, they are involved in our metabolism, immune function, sexual reproduction, and growth. Hormones are made by specialized groups of cells within the body’s glands. The glands—such as the pituitary, thyroid, adrenals, ovaries, and testes—release hormones into the body as needed to stimulate, regulate, and control the function of other various tissues and organs involved in biological processes.

We cannot survive without hormones. As children, hormones help us “grow up.” In teenagers, they drive puberty. As we get older, some of our hormone levels naturally decline. But what does that mean? Scientists do not know exactly. In order to know more, NIA investigates how replenishing hormones in older people affects frailty and function. Many of these studies focus on hormones that decline with age, including:

• Growth hormone
• Melatonin
• Dehydroepiandrosterone (DHEA)
• Testosterone
• Estrogen and progesterone (as part of menopausal hormone therapy)

How Hormones Work

Most hormones are typically found in very low concentrations in the bloodstream. But a hormone’s concentration will fluctuate depending on the body’s activity. Like a key that unlocks a door, a hormone molecule is released by a gland and travels through the blood until it finds a cell with the right fit, a “receptor.” The hormone latches onto a cell’s receptor and a signal is sent into the cell. These signals may instruct the cell to multiply, make proteins or enzymes, or perform other vital tasks. Some hormones can even cause a cell to release other hormones.

One hormone may fit with many types of cells but may not affect all cells in the same way. For example, one hormone may stimulate one cell to perform a task but it might also turn off a different cell. Additionally, how a cell responds to a hormone may change throughout life.

For more information on health and aging, contact:

National Institute on Aging Information Center
P.O. Box 8057
Gaithersburg, MD 20898-8057
800-222-2225 (toll-free)
800-222-4225 (TTY/toll-free)
www.nia.nih.gov

Treatments for Aging Hands

Because of sun and weather exposure, years of minor scrapes and cuts, and for some, constant exposure to water and detergents, our hands sometimes age faster than other parts of our bodies, and detract from our appearance. Fortunately is it now possible to rejuvenate the hands, restoring their appearance and sometimes also improving the thickness and health of the skin on the backs of the hands.

Fun loving, hard working hands don’t get the sun protection they need. The backs of the hands are sometimes overlooked when sunscreen is applied - or the sunscreen is washed off or accidentally wiped away. Gardening gloves, golf gloves, bike gloves work gloves can help to protect our hands from sun and from trauma.

Daily moisturizing your hands is critical to keep your skin supple and prevent dryness and cracking. Wearing gloves and moisturizing in the cold weather helps protect your hands from chapping and cracking.

For some people, dry cracked hands are a chronic condition called contact dermatitis, or hand eczema. Often caused by your daily routine, one which involves constantly having wet hands (i.e. hairdresser, surgeon, homemaker), this condition results in red, scaly, and very itchy hands. If you suspect your have this, read more at http://www.eczemaguide.ca/basics/eczema_like/hand_eczema_hand_dermatitis.html

There are some solutions to rejuvenating the look and feel of your hands:

• There are numerous special hand creams available, more being introduced almost every week! Creams with vitamins A, C, E and alpha hydroxyl acids are key ingredients which can help prevent and restore your youthful looking hands.
• Restisol-A® 0.01% cream contains tretinoin (which prevents and corrects some aspects of sun damage) and also has an SPF 15 sunscreen. When Retisol-A cream is applied to exposed areas like the face and the backs of the hands EVERY morning - year after year - the aging process is slowed down, and sometimes after a year or two the skin will actually start to look and feel younger and healthier.
• Sunscreens which have the ability to stick to the skin (for example, Anthelios-45® Waterproof Sunscreen) can be very helpful on active parts of the body like the hands, and can also act as a moisturizer. The sunscreen should be applied before sun exposure, even if you are using Retisol-A as a base coat for your skin every morning.

When the skin on the back of the hands has become old looking and freckled - and sometimes also thinned out - it is possible to correct these problems and give your hands a fresh, more youthful look:

• Brown spots (sometimes called freckles, “age spots” or “liver spots”) can be faded using fading creams and also by using the Medlite C6 laser. Treatments take only a few minutes, are well tolerated, and great improvement is usually obvious within a couple of weeks.
• Thin skin on the backs of the hands can be quickly improved by treatment with Restylane™. This not only improves the appearance of the hands by making veins and bones less obvious, but also restores the fullness found in youthful skin and gives some protection against bumps and bruises. The benefits of a single treatment can be seen immediately and often last 6-12 months, sometimes longer.
• In some cases Artecoll™ can also be used to improve the thickness of the skin on the backs of the hands. Artecoll™ costs more to use, and several treatment sessions 2-4 months apart may be required, but Artecoll™ has the advantage of producing an improvement which can last for many years.

Like most things, prevention is your best solution. Keep your hands beautiful by remembering to moisturize, use a sunblock and protect your hands from exposure - the same way you look after your face. For more information on cleansers, moisturizers, sunscreens, and general skincare, go to SkinCareGuide.ca.

About the author:
Dr. Kevin Smith is a dermatologist in Niagara Falls, Ontario with a particular interest in protecting the skin and in correcting skin problems resulting from aging, rosacea and sun damage. He is an expert in the use of Botox®, fillers, lasers and intense pulsed light to maintain and enhance the appearance of the skin, and have lectured on those subjects across North America, and in Europe, Asia and Mexico. Read more at www.smithlaser.com

The Benefits of Anti Aging Facial Masks

Skin wrinkles are caused by two main factors: heredity and the environment. There is little you can do about heredity and the natural aging process, but there is something you can do about the other causes. Pollution in the environment, sun exposure and stress can all lead to premature aging of the skin. Using anti aging creams is beneficial for reducing the appearance of wrinkles. The creams are even more effective when combined with regular facials. Read more

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